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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Nazartinib||EGF816|EGF-816||EGFR Inhibitor 3rd gen 25||Nazartinib (EGF816) is a third generation EGFR inhibitor with selectivity towards mutant forms of EGFR, resulting in inhibition of tumor cell growth (PMID: 27433829, PMID: 31954624).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT02108964||Phase Ib/II||Nazartinib||A Phase I/II, Multicenter, Open-label Study of EGFRmut-TKI EGF816, Administered Orally in Adult Patients With EGFRmut Solid Malignancies||Active, not recruiting||USA | ESP | DEU | CAN||5|