Therapy Detail

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Therapy Name ATP128 + Ezabenlimab + VSV-GP128
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ATP128 ATP 128|ATP-128 ATP128 is a chimeric protein vaccine that potentially modify antigen presentation of dendritic cells, leading to activation of immune response against tumor cells (NCI Drug Dictionary).
Ezabenlimab BI754091|BI-754091|BI 754091 Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117 Ezabenlimab (BI 754091) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (J Clin Oncol. 36, no. 5_suppl (February 2018) 212-212).
VSV-GP128 VSVGP128|VSV GP128|VSVGP 128|VSVGP-128 VSV-GP128 is a chimeric vesicular stomatitis virus (VSV) viral vector-based cancer vaccine containing tumor-associated antigen peptides, which potentially results in immune modulation and tumor cell killing (NCI Thesaurus).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04046445 Phase Ib/II ATP128 + Ezabenlimab ATP128 ATP128 + Ezabenlimab + VSV-GP128 Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01) Active, not recruiting USA | DEU | BEL 1


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