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mRNA-4359 is an mRNA-based cancer vaccine targeting IDO and PD-L1, which potentially increases cytotoxic T-cell response against tumor cells (NCI Thesaurus).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|mRNA-4359||mRNA 4359|mRNA4359||mRNA-4359 is an mRNA-based cancer vaccine targeting IDO and PD-L1, which potentially increases cytotoxic T-cell response against tumor cells (NCI Thesaurus).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT05533697||Phase Ib/II||mRNA-4359 + Pembrolizumab mRNA-4359||Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors||Recruiting||USA | GBR | ESP | AUS||0|