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Therapy Name | KFA115 + Tislelizumab |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
KFA115 | KFA-115|KFA 115|NVP-KFA115|NVPKFA115|NVP KFA115 | Limited information is currently available on KFA115 (May 2023). | ||
Tislelizumab | BGB-A317 | Immune Checkpoint Inhibitor 146 PD-L1/PD-1 antibody 110 | Tislelizumab (BGB-A317) is a human monoclonal antibody that targets PD-1 (PDCD1), thereby blocking the binding of PD-L1 (CD274) and potentially resulting in activation of a T-cell immune response against tumor cells (PMID: 32769013, PMID: 32561638, PMID: 32540858). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05544929 | Phase I | KFA115 + Tislelizumab KFA115 | A Study of Safety and Efficacy of KFA115 Alone and KFA115 in Combination With Tislelizumab in Patients With Select Advanced Cancers | Recruiting | USA | CAN | 3 |