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Therapy Name | SGI-1027 |
Synonyms | |
Therapy Description |
SGI-1027 binds and inhibits DNMT1, DNMT3A, and DNMT3B, which leads to decreased DNA methylation and may result the activation of silenced tumor suppressor genes (PMID: 19417133, PMID: 30344731). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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SGI-1027 | SGI 1027 | DNMT inhibitor (Pan) 5 | SGI-1027 binds and inhibits DNMT1, DNMT3A, and DNMT3B, which leads to decreased DNA methylation and may result the activation of silenced tumor suppressor genes (PMID: 19417133, PMID: 30344731). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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