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|Therapy Name||Anastrozole + Letrozole|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Anastrozole||Arimidex||Anastrozol||Aromatase Inhibitor 3||Arimidex (anastrozole) is an aromatase inhibitor, which inhibits estrogen synthesis (PMID: 29719441). Arimidex (anastrozole) is FDA approved for postmenopausal women with hormone receptor-positive early breast cancer or advanced patients who have failed tamoxifen therapy (FDA.gov).|
|Letrozole||Femara||Letrozol||Aromatase Inhibitor 3||Femara (letrozole) is an aromatase inhibitor, which inhibits estrogen synthesis, and is approved for postmenopausal women with hormone receptor positive breast cancer (FDA.gov).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT04294225||Phase II||Anastrozole + Letrozole||Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer||Recruiting|
|NCT02246621||Phase III||Abemaciclib + Anastrozole + Letrozole Anastrozole + Letrozole||A Study of Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer||Active, not recruiting|