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Therapy Name Peginterferon alfa-2b
Synonyms
Therapy Description

Sylatron (peginterferon alfa-2b) is polyethylene glycol (PEG)-conjugated recombinant interferon alpha, subtype 2b, which may have antitumor activity (PMID: 23002124, PMID: 16953837, PMID: 24741445).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Peginterferon alfa-2b Sylatron PEG-IFN Sylatron (peginterferon alfa-2b) is polyethylene glycol (PEG)-conjugated recombinant interferon alpha, subtype 2b, which may have antitumor activity (PMID: 23002124, PMID: 16953837, PMID: 24741445).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status
NCT02737046 Phase II Interferon alpha-2b Peginterferon alfa-2b Belinostat + Zidovudine Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma Recruiting
NCT01964300 Phase II Peginterferon alfa-2b Peginterferon Alfa-2b in Treating Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery Terminated
NCT02038036 Phase III Peginterferon alfa-2b Anagrelide Hydroxyurea Pipobroman Ruxolitinib Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. (RESPONSE-2) Completed
NCT02089685 Phase Ib/II Ipilimumab Peginterferon alfa-2b Pembrolizumab Safety and Tolerability of Pembrolizumab (MK-3475) + Pegylated Interferon Alfa-2b and Pembrolizumab+ Ipilimumab in Participants With Advanced Melanoma or Renal Cell Carcinoma (MK-3475-029/KEYNOTE-29) Active, not recruiting


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