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Therapy Name | ON044580 |
Synonyms | |
Therapy Description |
ON044580 is a non-ATP competitive inhibitor of BCR-ABL, BCR-ABL (T315I), JAK2, and JAK2(V617F), which may inhibit cell proliferation through inhibition of STAT5 signaling (PMID: 20717479, PMID: 20798787). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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ON044580 | SB17191|ON-044580 | BCR-ABL Inhibitor 31 JAK2 Inhibitor 16 | ON044580 is a non-ATP competitive inhibitor of BCR-ABL, BCR-ABL (T315I), JAK2, and JAK2(V617F), which may inhibit cell proliferation through inhibition of STAT5 signaling (PMID: 20717479, PMID: 20798787). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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