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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|PI-3065||PIK3CD inhibitor 24||PI-3065 inhibits PIK3CD, which may block activation of the PI3K signaling pathway and inhibit tumor cell proliferation (PMID: 24919154, PMID: 28851839).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||pancreatic ductal adenocarcinoma||not applicable||PI-3065||Preclinical||Actionable||In a preclinical study, treatment with the PIK3-delta inhibitor PI-3065 resulted in increased host anti-tumor immune response and led to prolonged survival and decreased metastasis in an mouse model of KRAS G12D and TP53 R175H-expressing pancreatic ductal adenocarcinoma (PMID: 24919154).||24919154|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|