Therapy Detail

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Therapy Name ADXS11-001
Synonyms
Therapy Description

Lovaxin C (ADXS11-001) is an attenuated Listeria monocytogenes expressing HPV 16 E7 which may induce cytotoxic immune response against tumor cells expressing HPV 16 E7 (PMID: 25483687).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ADXS11-001 Lovaxin C Lovaxin C (ADXS11-001) is an attenuated Listeria monocytogenes expressing HPV 16 E7 which may induce cytotoxic immune response against tumor cells expressing HPV 16 E7 (PMID: 25483687).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status
NCT02002182 Phase II ADXS11-001 ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer Active, not recruiting
NCT02399813 Phase Ib/II ADXS11-001 Phase 2 Study of ADXS11-001 in Subjects With Anal Cancer or Cancer of the Rectum Completed
NCT02853604 Phase III ADXS11-001 Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer (AIM2CERV) Active, not recruiting
NCT02164461 Phase Ib/II ADXS11-001 ADXS11-001 High Dose HPV+ Cervical Cancer Completed
NCT02291055 Phase Ib/II Durvalumab ADXS11-001 Phase 1-2 Study of ADXS11-001 or MEDI4736 Alone or Combo In Cervical or HPV+ Head & Neck Cancer Active, not recruiting


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