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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SKF-96365||SKF 96365|SKF96365||SKF-96365 is a non-specific inhibitor of store-operated calcium entry, leading to cell-cycle arrest and suppression of tumor cell growth (PMID: 23383239, PMID: 20590636, PMID: 26803057).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||colorectal cancer||not applicable||SKF-96365||Preclinical - Cell line xenograft||Actionable||In a preclinical study, SKF-96365 treatment inhibited the calcium/calmodulin dependent protein kinase signaling leading to decreased proliferation and increased apoptosis of human colorectal cancer cells in culture and had moderate anti-cancer activity in cell line xenograft models (PMID: 26803057).||26803057|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|