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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SH-1242||HSP90 Inhibitor 35||SH-1242 is an analog of deguelin that binds the C-terminus of Hsp90 and inhibits its function, resulting in decreased tumor cell growth (PMID: 26645561).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||lung non-small cell carcinoma||not applicable||SH-1242||Preclinical - Pdx & cell culture||Actionable||In a preclinical study, SH-1242 inhibited growth of several non-small cell lung cancer (NSCLC) cell lines in culture, including cell lines with acquired drug resistance, and inhibited tumor growth in cell line and patient-derived xenograft models (PMID: 26645561).||26645561|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|