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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|WNT-C59||WNT Inhibitor 10||WNT-C59 is a small molecule inhibitor of PORCN, which subsequently inhibits Wnt/beta-catenin signaling and thus, may result in tumor growth reduction (PMID: 25980501, PMID: 32279067).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||nasopharynx carcinoma||not applicable||WNT-C59||Preclinical||Actionable||In a preclinical study, nasopharynx carcinoma cells treated with WNT-C59 in culture and mouse models demonstrated inhibition of the Wnt signaling pathway and suppression of tumor growth (PMID: 25980501).||25980501|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|