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|Therapy Name||CCT007093 + Nutlin-3|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|CCT007093||PPM1D Inhibitor 3||CCT007093 is a small molecule inhibitor of PPM1D, which induces phosphorylation of P38 and thereby may result in cell growth inhibition (PMID: 17700519).|
|Nutlin-3||Nutlin|Nutlin-3a||MDM2 Inhibitor 20||Nutlin-3 is an MDM2 inhibitor which activates p53 and results in cancer cells undergoing apoptosis and cellular senescence. Nutlin-3 is a candidate for neoadjuvant therapy in cancers with a functional p53 (PMID: 18451145).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|