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OPB-51602 is a small molecule inhibitor of Stat3 that demonstrates antitumor activity (Mol Cancer Ther November 2013 12; C180 ).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|OPB-51602||STAT3 Inhibitor 19||OPB-51602 is a small molecule inhibitor of Stat3 that demonstrates antitumor activity (Mol Cancer Ther November 2013 12; C180, PMID: 25912076).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||hematologic cancer||no benefit||OPB-51602||Phase I||Actionable||In a Phase I trial, OPB-51602 treatment resulted in no objective response and stable disease in 15% (3/20) of patients with hematological malignancies (PMID: 25912076).||25912076|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|