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X480 is a dual PI3K/mTOR inhibitor, which may lead to decreased tumor growth and metastasis (Eur J Cancer, 2012, 48, S5:235).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|X480||mTOR Inhibitor 51 PI3K Inhibitor (Pan) 37||X480 is a dual PI3K/mTOR inhibitor, which may lead to decreased tumor growth and metastasis (Eur J Cancer, 2012, 48, S5:235, PMID: 29687745).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||prostate cancer||not applicable||X480||Preclinical - Cell line xenograft||Actionable||In a preclinical study, treatment with X480 in prostate cancer cell lines resulted in reduced cell proliferation and induced apoptotic activity in culture, and decreased tumor load and metastasis in cell line xenograft models (Eur J Cancer, 2012, 48, S5:235).||detail...|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|