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4SC-205 inhibits human kinesin-related motor protein Eg5, which may lead to cell cycle arrest and apoptosis in tumor cells (NCI Drug Dictionary).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|4SC-205||LH031||4SC-205 inhibits human kinesin-related motor protein Eg5, which may lead to cell cycle arrest and apoptosis in tumor cells (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||4SC-205||Phase I||Actionable||In a Phase I trial, 4SC-205 treatment demonstrated safety and promising long-term disease stabilization in patients with advanced solid tumors, resulted in a median time on study of 162 days in patients receiving continuous dosing (J Clin Oncol (Meeting Abstracts) May 2015 vol. 33 no. 15_suppl 2528).||detail...|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|