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Drug Name Trade Name Synonyms Drug Classes Drug Description
BKT140 TN14003|BL-8040|BL8040|Motixafortide CXCR4 Inhibitor 15 BL-8040 (BKT140) is a selective CXCR4 antagonist that prevents SDF-1 (CXCL12) binding, which may lead to decreased tumor growth (PMID: 21138752).
Cyclosporine Sandimmune Ciclosporin
Methylprednisolone Artisone-Wyeth 6alpha-Methylprednisolone
anti-thymocyte globulin Thymoglobulin lymphocyte immune globulin|ATGAM Thymoglobulin (anti-thymocyte globulin) is an immunoglobulin that binds to and destroys T-lymphocytes, which may aid in reduction of graft-vs-host disease when administered with stem cell transplantation (PMID: 32624582).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02462252 Phase II anti-thymocyte globulin + BKT140 + Cyclosporine + Methylprednisolone Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome Completed USA 0


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