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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|MitoMet-10||MitoMet-10 is a mitochondria-targeted analog of Metformin with increased potency, which may decrease tumor cell proliferation and increase sensitivity to radiotherapy (PMID: 27216187).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||pancreatic cancer||not applicable||MitoMet-10||Preclinical||Actionable||In a preclinical study, MitoMet-10 decreased tumor growth in mouse models of pancreatic cancer (PMID: 27216187).||27216187|
|Unknown unknown||pancreatic ductal adenocarcinoma||not applicable||MitoMet-10||Preclinical||Actionable||In a preclinical study, MitoMet-10 inhibited mitochondrial function and proliferation of pancreatic ductal adenocarcinoma cells in culture, and demonstrated increased potency compared to metformin (PMID: 27216187).||27216187|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|