Therapy Detail

Therapy Name Poloxin-2
Synonym
Therapy Description

Poloxin-2, an analog of Poloxin, is a small molecule inhibitor of PLK1, which may result in apoptotic activity and induction of cell-cycle arrest (PMID: 26279064).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Poloxin-2 PLK1 Inhibitor 16 Poloxin-2, an analog of Poloxin, is a small molecule inhibitor of PLK1, which may result in apoptotic activity and induction of cell-cycle arrest (PMID: 26279064).
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable Poloxin-2 Preclinical - Cell culture Actionable In a preclinical study, human cancer cells demonstrated sensitivity to treatment with Poloxin-2 in culture, resulting in cell-cycle arrest and apoptotic induction (PMID: 26279064). 26279064
Clinical Trial Phase Therapies Title Recruitment Status