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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|M-COPA||AMF-26||M-COPA is a small-molecule that inhibits Arf1 activation, which interferes with function of the Golgi apparatus and leads to decreased tumor growth (PMID: 27197184, PMID: 31484543).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR2 amp||gastric signet ring cell adenocarcinoma||sensitive||M-COPA||Preclinical - Cell culture||Actionable||In a preclinical study, treatment with M-COPA resulted in decreased Fgfr2 cell surface expression and phosphorylation and reduced growth of an FGFR2-amplified signet cell gastric cancer cell line in culture (PMID: 27197184).||27197184|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|