Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Pyr1||Pyr1 inhibits LIM kinase (LIMK), potentially resulting in decreased tumor cell proliferation and tumor growth (PMID: 27216191, PMID: 30550596).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||breast cancer||not applicable||Pyr1||Preclinical - Cell line xenograft||Actionable||In a preclinical study, Pyr1 inhibited proliferation and migration of breast cancer cell lines in culture, and inhibited growth of primary tumors and metastases in breast cancer cell line xenograft models (PMID: 27216191).||27216191|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|