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|Therapy Name||PLX4720 + SGX523|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|PLX4720||PLX-4720|PLX 4720||BRAF Inhibitor 20||PLX4720 is a 7-azaindole derivative and RAF kinase inhibitor with greater affinity for BRAF V600E than BRAF wild-type, which may induce cell cycle arrest and apoptosis, and lead to tumor growth inhibition and regression (PMID: 18287029).|
|SGX523||SGX-523||MET Inhibitor 53||SGX523 is a highly selective, ATP-competitive inhibitor of MET that blocks Met signaling, resulting in cell death in tumor cells (PMID: 19934279).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|