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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|LDC1267||AXL Inhibitor 27 MERTK Inhibitor 9 TYRO3 Inhibitor 8||LDC1267 is a specific TAM kinase inhibitor, with activity against TYRO3, AXL, and MERTK, which potentially enhances anti-tumor immune response and decreases tumor metastasis (PMID: 24553136).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||breast cancer||not applicable||LDC1267||Preclinical||Actionable||In a preclinical study, LDC1267 treatment resulted in reduced l metastatic liver lesions, but did not impact primary tumor growth, in a mouse model of metastatic breast cancer (PMID: 24553136).||24553136|
|Unknown unknown||melanoma||not applicable||LDC1267||Preclinical||Actionable||In a preclinical study, LDC1267 treatment resulted in decreased metastasis in a mouse model of metastatic melanoma (PMID: 24553136).||24553136|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|