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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|NHS-IL12||M9241|M-9241||NHS-IL12 (M9241) is an immunocytokine composed of IL-12 linked to human tumor necrosis factor targeted IgG1, which may result in enhanced anti-tumor immune response (PMID: 24681847).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT05361798||Phase II||NHS-IL12||T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High- and Intermediate-Risk Prostate Cancer Treated With Androgen Deprivation Therapy||Recruiting||USA||0|
|NCT04303117||Phase Ib/II||NHS-IL12 M7824 + NHS-IL12||NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma||Recruiting||USA||0|
|NCT01417546||Phase I||NHS-IL12||NHS-IL12 for Solid Tumors||Completed||USA||0|