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Therapy Name | CCG-203971 |
Synonyms | |
Therapy Description |
CCG-203971 is a small molecule inhibitor that blocks the activity and nuclear localization of MRTF-A, thereby possibly resulting in mitigation of cell migration and metastasis, and decreased tumor growth (PMID: 27837031). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
CCG-203971 | CCG-203971 is a small molecule inhibitor that blocks the activity and nuclear localization of MRTF-A, thereby possibly resulting in mitigation of cell migration and metastasis, and decreased tumor growth (PMID: 27837031, PMID: 32665796). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Unknown unknown | melanoma | not applicable | CCG-203971 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, a melanoma cell line treated with CCG-203971 resulted in inhibition of cell migration, invasion, and decreased cell growth in culture, and a reduced tumor burden in xenograft models (PMID: 27837031). | 27837031 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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