Therapy Detail
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| Therapy Name | MEDI3726 |
| Synonyms | |
| Therapy Description |
MEDI3726 (ADCT-401) is an antibody-drug conjugate consisting of a monoclonal antibody that targets prostate specific membrane antigen and the cytotoxic agent, pyrrolobenzodiazepine (AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3111A, PMID: 32459957, PMID: 30065100). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MEDI3726 | ADCT-401|ADCT401|MEDI-3726|MEDI 3726 | PSMA Antibody 20 | MEDI3726 (ADCT-401) is an antibody-drug conjugate consisting of a monoclonal antibody that targets prostate specific membrane antigen and the cytotoxic agent, pyrrolobenzodiazepine (AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3111A, PMID: 32459957, PMID: 30065100). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02991911 | Phase I | Enzalutamide + MEDI3726 MEDI3726 | A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer | Completed | USA | GBR | 1 |
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