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Therapy Name MEDI3726
Synonyms
Therapy Description

MEDI3726 (ADCT-401) is an antibody-drug conjugate consisting of a monoclonal antibody that targets prostate specific membrane antigen and the cytotoxic agent, pyrrolobenzodiazepine (AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3111A).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
MEDI3726 ADCT-401|ADCT401|MEDI-3726|MEDI 3726 PSMA Antibody 12 MEDI3726 (ADCT-401) is an antibody-drug conjugate consisting of a monoclonal antibody that targets prostate specific membrane antigen and the cytotoxic agent, pyrrolobenzodiazepine (AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3111A, PMID: 32459957, PMID: 30065100).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02991911 Phase I Enzalutamide + MEDI3726 MEDI3726 A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer Completed USA 2


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