Therapy Detail

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Therapy Name EGFR(V)-EDV-Dox
Synonyms
Therapy Description

EGFR(V)-EDV-Dox is a formulation of EGFR bispecific antibodies coupled with nanocellular compounds containing therapeutic dose of doxorubicin, which delivers the cytotoxic doxorubicin to tumor cells over expressing EGFR, leading to anti-tumor activities (PMID: 26279503).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
EGFR(V)-EDV-Dox EGFR Antibody 39 EGFR(V)-EDV-Dox is a formulation of EGFR bispecific antibodies coupled with nanocellular compounds containing therapeutic dose of doxorubicin, which delivers the cytotoxic doxorubicin to tumor cells over expressing EGFR, leading to anti-tumor activities (PMID: 26279503).

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  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02766699 Phase I EGFR(V)-EDV-Dox A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent Glioblastoma Multiforme (GBM) (CerebralEDV) Unknown status USA 0


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