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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|CG200745||HDAC Inhibitor 38||CG200745 is an HDAC inhibitor, which increases tumor cell apoptosis and decreases tumor cell growth (PMID: 25781604, PMID: 28134290).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||CG200745||Phase I||Actionable||In a Phase I trial, CG200745 treatment demonstrated safety in advanced solid tumor patients and did not result in any partial or complete responses, but led to stable disease in 57.1% (16/28) of patients for at least six weeks (PMID: 26076682).||26076682|
|Unknown unknown||pancreatic cancer||not applicable||CG200745||Preclinical - Cell culture||Actionable||In a preclinical study, CG200745 decreased viability of pancreatic cancer cell lines in culture, including Gemzar (gemcitabine)-resistant cell lines (PMID: 28134290).||28134290|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|