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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|A-674563||Akt1 Inhibitor 6||A-674563 is an inhibitor of AKT1, which may result in induction of apoptotic activity and inhibition of tumor growth (PMID: 26970307).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||melanoma||not applicable||A-674563||Preclinical - Cell line xenograft||Actionable||In a preclinical study, a melanoma cell line demonstrated sensitivity to A-674563, resulting in apoptotic activity and inhibition of Akt1 activity in culture, and inhibition of tumor growth in xenograft models (PMID: 26970307).||26970307|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|