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Therapy Name MEDI9197
Synonyms
Therapy Description

MEDI9197 acts an an agonist for the TLR7 and TLR8, potentially resulting in increased anti-tumor immune response (J Clin Oncol 34, 2016 (suppl; abstr TPS3095)).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
MEDI9197 MEDI-9197|MEDI 9197|Telratolimod|3M-052|3M 052 TLR7 Agonist 8 TLR8 Agonist 7 MEDI9197 (telratolimod) acts an an agonist for the TLR7 and TLR8, potentially resulting in increased anti-tumor immune response (J Clin Oncol 34, 2016 (suppl; abstr TPS3095), PMID: 31511088).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02556463 Phase I MEDI9197 Durvalumab + MEDI9197 A Study of MEDI9197 in Subjects With Solid Tumors or CTCL and in Combination With Durvalumab and Palliative Radiation in Subjects With Solid Tumors Terminated USA | FRA | CAN 0


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