Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|MBQ-167||MBQ-167 inhibits Rac1 and Cdc42, resulting in decreased downstream signaling, increased cell-cycle arrest, and reduced tumor growth and metastasis (PMID: 28450422).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||breast cancer||not applicable||MBQ-167||Preclinical - Cell line xenograft||Actionable||In a preclinical study, MBQ-167 increased cell-cycle arrest and decreased viability and migration of breast cancer cell lines in culture, and reduced tumor growth and metastasis in a breast cancer cell line xenograft model (PMID: 28450422).||28450422|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|