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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|LY900009||Gamma secretase inhibitor 12||LY900009 inhibits gamma secretase, resulting in decreased Notch signaling and potentially leading to reduced tumor growth (PMID: 26798966).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||LY900009||Phase I||Actionable||In a Phase I trial, LY900009 demonstrated manageable safety and some preliminary activity in patients with advanced solid tumors, with treatment resulting in no responses, but stable disease in 14% (5/35) of patients (PMID: 26798966).||26798966|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|