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SC-006 is an antibody drug conjugate consisting of a monoclonal anti-tumor-associated antigen (TAA) antibody in conjugation with a cytotoxic agent, which may selectively kill TAA-positive cancer cells (NCI Drug Dictionary).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SC-006||SC006|SC 006||SC-006 is an antibody-drug conjugate (ADC) comprising an antibody targeted against RNF43 linked to a DNA crosslinking agent, with potential antitumor activity (Cancer Res (2020) 80 (16_Supplement): CT167).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT03035279||Phase I||SC-006||A Study of SC-006 in Subjects With Advanced Cancer||Terminated||USA||0|