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Therapy Name | ETP-46464 + Radiotherapy |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
ETP-46464 | ETP46464 | ATR Inhibitor 12 | ETP-46464 inhibits ATR, potentially resulting in increased tumor cell sensitivity to other anti-cancer agents (PMID: 25560806, PMID: 21552262). | |
Radiotherapy |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | cervical cancer | not applicable | ETP-46464 + Radiotherapy | Preclinical - Cell culture | Actionable | In a preclinical study, ETP-46464 increased the sensitivity of cervical cancer cell lines to ionizing radiation in culture (PMID: 25560806). | 25560806 |
Unknown unknown | endometrial cancer | not applicable | ETP-46464 + Radiotherapy | Preclinical - Cell culture | Actionable | In a preclinical study, ETP-46464 increased the sensitivity of endometrial cancer cell lines to ionizing radiation in culture (PMID: 25560806). | 25560806 |
Unknown unknown | ovarian cancer | not applicable | ETP-46464 + Radiotherapy | Preclinical - Cell culture | Actionable | In a preclinical study, ETP-46464 increased the sensitivity of ovarian cancer cell lines to ionizing radiation in culture (PMID: 25560806). | 25560806 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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