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Therapy Name | Odronextamab |
Synonyms | |
Therapy Description |
Odronextamab (REGN1979) is a CD20/CD3 bispecific antibody, which targets CD20 expressing cells via T-cell activation, and subsequently leads to cell death (PMID: 26659273). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Odronextamab | REGN1979 | Odronextamab (REGN1979) is a CD20/CD3 bispecific antibody, which targets CD20 expressing cells via T-cell activation, and subsequently leads to cell death (PMID: 26659273). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02290951 | Phase I | Rituximab Odronextamab | Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies | Recruiting | USA | FRA | DEU | 2 |
NCT03888105 | Phase II | Odronextamab | Assess the Anti-Tumor Activity and Safety of REGN1979 in Patients With Relapsed or Refractory Follicular Lymphoma | Recruiting | USA | ITA | FRA | ESP | DEU | CAN | 8 |