Therapy Detail

Therapy Name G1T48
Therapy Description

G1T48 is an orally bioavailable selective inhibitor of estrogen receptor (ER) that leads to down-regulation of ER and growth inhibition of ER-positive tumor cells (Cancer Res 2017;77(13 Suppl):Abstract nr 5641).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
G1T48 G1T48 is an orally bioavailable selective inhibitor of estrogen receptor (ER) that leads to down-regulation of ER and growth inhibition of ER-positive tumor cells (Cancer Res 2017;77(13 Suppl):Abstract nr 5641).
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Clinical Trial Phase Therapies Title Recruitment Status
NCT03455270 Phase I G1T48 G1T48, an Oral SERD, in ER-Positive, HER2-Negative Advanced Breast Cancer Recruiting