Therapy Detail

Therapy Name ST-162 + unspecified PD-1 antibody
Synonym
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ST-162 ST-162 is a dual kinase inhibitor of MAPK and PI3K signaling, which may result in decreased phosphorylation of Akt and Erk and subsequent tumor regression (PMID: 28775144).
unspecified PD-1 antibody Experimental PD-1 antibody PD-L1/PD-1 antibody 50
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer predicted - sensitive ST-162 + unspecified PD-1 antibody Preclinical Actionable In a preclinical study, ST-162 therapy combined with an anti-PD-1 antibody resulted in greater tumor growth inhibition than treatment with either agent alone in a colorectal cancer mouse model (PMID: 28775144). 28775144
Clinical Trial Phase Therapies Title Recruitment Status