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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|DTS-108||TOPO1 inhibitor 8||DTS-108 is an oligopeptide in conjugation with the topoisomerase I inhibitor SN-38 that may inhibit proliferation and induce apoptosis in tumor cells (PMID: 27920527).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||DTS-108||Phase I||Actionable||In a Phase I trial, DTS-108 demonstrated safety and preliminary efficacy, resulting in stable disease in 21% (9/42) of patients with advanced solid tumors (PMID: 27920527).||27920527|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|