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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|BMS-536924||IGF-1R Inhibitor 17||BMS-536924 is an ATP-competitive inhibitor of IGF-1R and IR, which induces tumor cell apoptosis and decreases tumor growth (PMID: 25897243).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ETV6 - NTRK3||Advanced Solid Tumor||sensitive||BMS-536924||Preclinical||Actionable||In a preclinical study, transformed human cells expressing ETV6-NTRK3 were sensitive to BMS-536924, demonstrating a reduction in both cell survival and transformation activity in culture (PMID: 21804605).||21804605|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|