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|Therapy Name||OBI-821 + OBI-833|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|OBI-821||OBI821|OBI 821||OBI-821 is a natural saponin derived from the soapbark tree, Quillaja saponaria Molina, which when combined with a vaccine may help promote a cytotoxic T-cell response against tumor cells (PMID: 32718986).|
|OBI-833||Globo H-CRM197 vaccine||OBI-833 is a vaccine consists of the Globo H hexasaccharide 1 (Globo H) antigen conjugated to DT-CRM197, which may stimulate anti-tumor immune response (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT02310464||Phase I||OBI-821 + OBI-833||Trial of Active Immunotherapy With OBI-833 (Globo H-CRM197) in Advanced/Metastatic Gastric, Lung, Colorectal or Breast Cancer Subjects||Completed||1|