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Therapy Name VIP152
Synonyms
Therapy Description

BAY 1251152 is a selective inhibitor of P-TEFb/CDK9, which may lead to blockade of MCL1 and MYC transcription, resulting in antitumor activity (J Clin Oncol 36, 2018 (suppl; abstr 2507).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
VIP152 BAY 1251152|BAY1251152|BAY-1251152|VIP-152 CDK9 Inhibitor 19 VIP152 (BAY 1251152) selectively inhibits CDK9, potentially resulting in antitumor activity (PMID: 35046056, PMID: 32488087).

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  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02635672 Phase I VIP152 Phase I Dose Escalation Study for BAY 1251152 in Patients With Advanced Cancer Recruiting USA 1
NCT04978779 Phase I VIP152 A Study to Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome Recruiting USA 1


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