Therapy Detail

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Therapy Name HPN424
Synonyms
Therapy Description

HPN424 is an antibody that binds to CD3 on T-cells as well as PSMA, potentially resulting in increased immune response against PSMA-expressing tumor cells (Cancer Res July 1 2018 (78) (13 Supplement) 1773).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
HPN424 HPN-424|HPN 424 CD3 Antibody 56 PSMA Antibody 12 HPN424 is an antibody that binds to CD3 on T-cells as well as PSMA, potentially resulting in increased immune response against PSMA-expressing tumor cells (Cancer Res July 1 2018 (78) (13 Supplement) 1773).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03577028 Phase I HPN424 Study of HPN424 in Patients With Advanced Prostate Cancer Recruiting USA 1


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