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Therapy Name PF-06804103
Synonyms
Therapy Description

PF-06804103 is an antibody-drug conjugate comprising an ERBB2 (HER2)-targeting antibody linked to Aur0101, which delivers the cytotoxic drug to ERBB2 (HER2)-expressing tumor cells, potentially resulting in decreased growth of ERBB2 (HER2)-expressing tumors (Cancer Res July 1 2018 (78) (13 Supplement) 818).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
PF-06804103 PF06804103|PF 06804103 HER2 (ERBB2) Antibody 58 HER2 (ERBB2) Antibody-Drug Conjugate 19 PF-06804103 is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2)-targeting antibody linked to Aur0101, which delivers the cytotoxic drug to ERBB2 (HER2)-expressing tumor cells, potentially resulting in decreased growth of ERBB2 (HER2)-expressing tumors (Cancer Res July 1 2018 (78) (13 Supplement) 818, PMID: 32747418, PMID: 32710210).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03284723 Phase I Letrozole + Palbociclib + PF-06804103 PF-06804103 PF-06804103 Dose Escalation in HER2 Positive and Negative (Negative Only in Part 2) Solid Tumors Completed USA | ITA | ESP 3


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