Therapy Detail

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Therapy Name ASN002
Synonyms
Therapy Description

ASN002 inhibits SYN and JAK, leading to decreased downstream signaling and potentially resulting in decreased tumor cell proliferation and reduced tumor growth (Cancer Res Jul 1 2017 (77) (13 Supp) 4204).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ASN002 Gusacitinib|ASN-002|EN-3351|EN3351 JAK Inhibitor (Pan) 8 SYK Inhibitor 15 ASN002 (gusacitinib) inhibits SYN and JAK, leading to decreased downstream signaling and potentially resulting in decreased tumor cell proliferation and reduced tumor growth (Cancer Res Jul 1 2017 (77) (13 Supp) 4204).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02440685 Phase Ib/II ASN002 A Phase 1/2 Study To Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid Tumors Terminated USA 1
NCT04416516 Phase II ASN002 Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor Recruiting 1


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