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Therapy Name | INT230-6 |
Synonyms | |
Therapy Description |
INT230-6 is a therapy comprised of cisplatin and vinblastine plus a cell penetration excipient, which leads to improved uptake of the drug into cancer cells, potentially resulting in tumor regression as well as indirect antitumor effects (Cancer Res 2015;75(15 Suppl):Abstract nr 4295, PMID: 31646070). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
INT230-6 | INT 230-6|INT-230-6 | INT230-6 is a therapy comprised of cisplatin and vinblastine plus a cell penetration excipient, which leads to improved uptake of the drug into cancer cells, potentially resulting in tumor regression as well as indirect antitumor effects (Cancer Res 2015;75(15 Suppl):Abstract nr 4295, PMID: 31646070). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT03058289 | Phase Ib/II | INT230-6 INT230-6 + unspecified PD-1 antibody | A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 (IT-01) | Completed | USA | CAN | 0 |
NCT04781725 | Phase II | INT230-6 | Intratumoral INT230-6 in Breast Cancer | Unknown status | CAN | 0 |