Therapy Detail

Therapy Name IT-141
Therapy Description

IT-141 is composed of a polymer micelle, ITP-101, which contains the hydrophobic drug, SN-38, allowing greater solubility and potentially resulting in antitumor activity (PMID: 22187652).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IT-141 IT-141 is composed of a polymer micelle, ITP-101, which contains the hydrophobic drug, SN-38, allowing greater solubility and potentially resulting in antitumor activity (PMID: 22187652).
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable IT-141 Preclinical - Cell line xenograft Actionable In a preclinical study, colon cancer cell line xenograft models demonstrated tumor regression when treated with IT-141 (PMID: 22187652). 22187652
Clinical Trial Phase Therapies Title Recruitment Status
NCT03096340 Phase I IT-141 Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer Recruiting