Therapy Detail

Therapy Name IT-141
Synonyms
Therapy Description

IT-141 is composed of a polymer micelle, ITP-101, which contains the hydrophobic drug, SN-38, allowing greater solubility and potentially resulting in antitumor activity (PMID: 22187652).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IT-141 IT-141 is composed of a polymer micelle, ITP-101, which contains the hydrophobic drug, SN-38, allowing greater solubility and potentially resulting in antitumor activity (PMID: 22187652).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable IT-141 Preclinical - Cell line xenograft Actionable In a preclinical study, colon cancer cell line xenograft models demonstrated tumor regression when treated with IT-141 (PMID: 22187652). 22187652

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status
NCT03096340 Phase I IT-141 Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer Recruiting


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