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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|ODM-203||ODM203|ODM 203||FGFR Inhibitor (Pan) 24 VEGFR Inhibitor (Pan) 33||ODM-203 inhibits FGFR and VEGFR family members, potentially resulting in decreased tumor cell proliferation and decreased tumor growth (PMID: 30301864).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR1 amp||lung large cell carcinoma||sensitive||ODM-203||Preclinical - Cell line xenograft||Actionable||In a preclinical study, ODM-203 inhibited FGFR signaling and proliferation in a large cell lung cancer cell line with amplification of chromosome 8p12 leading to increased FGFR1 copy number, and inhibited tumor growth in xenograft models (PMID: 30301864).||30301864|
|FGFR2 amp||stomach cancer||sensitive||ODM-203||Preclinical - Cell line xenograft||Actionable||In a preclinical study, ODM-203 inhibited FGFR signaling and proliferation in a gastric cancer cell line with amplification of FGFR2, and inhibited tumor growth in xenograft models (PMID: 30301864).||30301864|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|