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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Tranylcypromine||Parnate||Dl-Tranylcypromine||KDM1A Inhibitor 12||Parnate (tranylcypromine) is a monoamine oxidase inhibitor (MAOI) that also inhibits Kdm1a (Lsd1), which may lead to inhibition of stem cell growth through epigenetic regulation (PMID: 26748182).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Ewing sarcoma||no benefit||Tranylcypromine||Preclinical - Cell culture||Actionable||In a preclinical study, Ewing sarcoma cell lines did not demonstrate sensitivity to Parnate (tranylcypromine) in culture (PMID: 29997151).||29997151|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|