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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|UNC0642||MP-IN-317||EHMT2 Inhibitor 4||UNC0642 (MP-IN-317) is a histone methyltransferase inhibitor that selectively inhibits EHMT2 (G9A) and EHMT1 (GLP), which may result in decreased methylation and potential cytotoxic effects against cancer cells (PMID: 24102134).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||breast cancer||not applicable||UNC0642||Preclinical - Cell culture||Actionable||In a preclinical study, UNC0642 decreased H3K9me2 levels, but did not inhibit colony formation in a breast cancer cell line in culture (PMID: 24102134).||24102134|
|Unknown unknown||pancreatic carcinoma||not applicable||UNC0642||Preclinical - Cell culture||Actionable||In a preclinical study, a pancreatic carcinoma cell line demonstrated sensitivity to UNC0642, resulting in inhibition of colony formation in culture (PMID: 24102134).||24102134|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|